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1

Pharmacokinetics and pharmacodynamics of mitragynine, the principle alkaloid of Mitragyna speciosa: present knowledge and future directions in perspective of pain

Ramachandram, Dinesh Sangarran, Damodaran, Thenmoly, Zainal, Hadzliana, Murugaiyah, Vikneswaran, Ramanathan, Surash

Journal:

Journal of Basic and Clinical Physiology and Pharmacology

Année:

2019

Langue:

english

Fichier:

PDF, 116 KB

english, 2019

2

Mechanisms of antihyperuricemic effect of Phyllanthus niruri and its lignan constituents

Vikneswaran Murugaiyah, Kit-Lam Chan

Journal:

Journal of Ethnopharmacology

Année:

2009

Langue:

english

Fichier:

PDF, 221 KB

english, 2009

3

Molecular docking studies and in vitro cholinesterase enzyme inhibitory activities of chemical constituents of Garcinia hombroniana

Jamila, Nargis, Yeong, Khaw Kooi, Murugaiyah, Vikneswaran, Atlas, Amir, Khan, Imran, Khan, Naeem, Khan, Sadiq Noor, Khairuddean, Melati, Osman, Hasnah

Journal:

Natural Product Research

Année:

2015

Langue:

english

Fichier:

PDF, 211 KB

english, 2015

4

Urinary NMR-based metabolomic analysis of rats possessing variable sperm count following orally administered Eurycoma longifolia extracts of different quassinoid levels

Ebrahimi, Forough, Ibrahim, Baharudin, Teh, Chin-Hoe, Murugaiyah, Vikneswaran, Chan, Kit-Lam

Journal:

Journal of Ethnopharmacology

Année:

2016

Langue:

english

Fichier:

PDF, 1.14 MB

english, 2016

5

Novel Acetylcholinesterase Inhibitors Identified from ZINC Database Using DockingâBased Virtual Screening for Alzheimer's Disease.

Ahmed Ali Abdusalam, Ashraf, Vikneswaran, Murugaiyah

Journal:

ChemistrySelect

Année:

2020

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2020

6

Developing a validated liquid chromatography–mass spectrometric method for the simultaneous analysis of five bioactive quassinoid markers for the standardization of manufactured batches of Eurycoma longifolia Jack extract as antimalarial medicaments

Chin-Hoe Teh, Vikneswaran Murugaiyah, Kit-Lam Chan

Journal:

Journal of Chromatography A

Année:

2011

Langue:

english

Fichier:

PDF, 2.04 MB

english, 2011

7

Analysis of lignans from Phyllanthus niruri L. in plasma using a simple HPLC method with fluorescence detection and its application in a pharmacokinetic study

Vikneswaran Murugaiyah, Kit Lam Chan

Journal:

Journal of Chromatography B

Année:

2007

Langue:

english

Fichier:

PDF, 356 KB

english, 2007

8

Anti-angiogenic activity of Gynura segetum leaf extracts and its fractions

Lay-Jing Seow, Hooi-Kheng Beh, Amin Malik Shah Abdul Majid, Vikneswaran Murugaiyah, Norhayati Ismail, Mohd Zaini Asmawi

Journal:

Journal of Ethnopharmacology

Année:

2011

Langue:

english

Fichier:

PDF, 914 KB

english, 2011

9

A simple HPLC–DAD method for the detection and quantification of psychotropic mitragynine in Mitragyna speciosa (ketum) and its products for the application in forensic investigation

Parthasarathy, Suhanya, Ramanathan, Surash, Murugaiyah, Vikneswaran, Hamdan, Mohammad Razak, Mohd Said, Mohd Ikram, Lai, Choon-Sheen, Mansor, Sharif Mahsufi

Journal:

Forensic Science International

Année:

2013

Langue:

english

Fichier:

PDF, 325 KB

english, 2013

10

Hypoglycemic and anti–hyperglycemic study of Gynura procumbens leaf extracts

Algariri, Khalid, Meng, Kuong Y, Atangwho, Item J, Asmawi, Mohd Z, Sadikun, Amirin, Murugaiyah, Vikneswaran, Ismail, Norhyati

Journal:

Asian Pacific Journal of Tropical Biomedicine

Année:

2013

Langue:

english

Fichier:

PDF, 655 KB

english, 2013

11

Anti-angiogenic activity of Morinda citrifolia extracts and its chemical constituents

Beh, Hooi-Kheng, Seow, Lay-Jing, Asmawi, Mohd Zaini, Abdul Majid, Amin Malik Shah, Murugaiyah, Vikneswaran, Ismail, Norhayati, Ismail, Zhari

Journal:

Natural Product Research

Année:

2012

Langue:

english

Fichier:

PDF, 124 KB

english, 2012

12

Flavonoids and phenylethanoid glycosides from Lippia nodiflora as promising antihyperuricemic agents and elucidation of their mechanism of action

Cheng, Lee-Chuen, Murugaiyah, Vikneswaran, Chan, Kit-Lam

Journal:

Journal of Ethnopharmacology

Année:

2015

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2015

13

Cholinesterase inhibitory activity of isoquinoline alkaloids from three Cryptocarya species (Lauraceae)

Wan Othman, Wan Nurul Nazneem, Liew, Sook Yee, Khaw, Kooi Yeong, Murugaiyah, Vikneswaran, Litaudon, Marc, Awang, Khalijah

Journal:

Bioorganic & Medicinal Chemistry

Année:

2016

Langue:

english

Fichier:

PDF, 574 KB

english, 2016

14

Hypoglycemic and anti-hyperglycemic study of Ocimum tenuiflorum L. leaves extract in normal and streptozotocin-induced diabetic rats

Mousavi, Leila, Salleh, Rabeta Mohd, Murugaiyah, Vikneswaran, Asmawi, Mohd Zaini

Journal:

Asian Pacific Journal of Tropical Biomedicine

Année:

2016

Langue:

english

Fichier:

PDF, 869 KB

english, 2016

15

AIP Conference Proceedings [AIP Publishing LLC THE 2015 UKM FST POSTGRADUATE COLLOQUIUM: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2015 Postgraduate Colloquium - Selangor, Malaysia (15–16 April 2015)] - Antibacterial activity of lichen Usnea rubrotincta, Ramalina dumeticola, and Cladonia verticillata

Gunasekaran, Saranyapiriya, Rajan, Vinoshene Pillai, Samsudin, Mohd. Wahid, Din, Laily, Ramanathan, Surash, Murugaiyah, Vikneswaran

Année:

2015

Langue:

english

Fichier:

PDF, 242 KB

english, 2015

16

in vivo anti- arthritic and anti-noceciptive effects of ethanol extract of Moringa oleifera leaves on complete Freund's adjuvant (CFA)-induced arthritis in rats

Mahdi, Harith Jameel, Khan, Nurzalina Abdul Karim, Asmawi, Mohd Zaini Bin, Mahmud, Roziahanim, Murugaiyah, Vikneswaran AL.

Journal:

Integrative Medicine Research

Année:

2017

Langue:

english

Fichier:

PDF, 308 KB

english, 2017

17

Autofluorescence study and selected cyanidin quantification in the Jewel orchids Anoectochilus sp. and Ludisia discolor

Poobathy, Ranjetta, Zakaria, Rahmad, Murugaiyah, Vikneswaran, Subramaniam, Sreeramanan, Ganapathi, T. R.

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 41.69 MB

english, 2018

18

Understanding the Physicochemical Properties of Mitragynine, a Principal Alkaloid of Mitragyna speciosa, for Preclinical Evaluation

Ramanathan, Surash, Parthasarathy, Suhanya, Murugaiyah, Vikneswaran, Magosso, Enrico, Tan, Soo, Mansor, Sharif

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 720 KB

english, 2015

19

Freeze-Dried Lopinavir-Loaded Nanostructured Lipid Carriers for Enhanced Cellular Uptake and Bioavailability: Statistical Optimization, in Vitro and in Vivo Evaluations

Khan, Arshad, Mudassir, Jahanzeb, Akhtar, Safia, Murugaiyah, Vikneswaran, Darwis, Yusrida

Journal:

Année:

2019

Langue:

english

Fichier:

PDF, 20.89 MB

english, 2019

20

Surface sterilization and micropropagation of Ludisia discolor

Poobathy, Ranjetta, Zakaria, Rahmad, Murugaiyah, Vikneswaran, Subramaniam, Sreeramanan

Journal:

Biocatalysis and Agricultural Biotechnology

Année:

2019

Langue:

english

Fichier:

PDF, 24.69 MB

english, 2019

21

Structural Reassignment of Koetjapic Acid following X-ray Crystallography and NMR Spectroscopy

Abubakar, Saifullah, Murugaiyah, Vikneswaran, Teh, Chin-Hoe, Chan, Kit-Lam

Journal:

Natural Product Communications

Année:

2017

Fichier:

PDF, 365 KB

2017

22

Apocynin and catalase prevent hypertension and kidney injury in Cyclosporine A-induced nephrotoxicity in rats

Tan, Yong Chia, Abdul Sattar, Munavvar, Ahmeda, Ahmad F., Abdul Karim Khan, Nurzalina, Murugaiyah, Vikneswaran, Ahmad, Ashfaq, Hassan, Zurina, Kaur, Gurjeet, Abdulla, Mohammed Hadi, Johns, Edward Jame

Journal:

Année:

2020

Fichier:

PDF, 7.35 MB

2020

23

The nootropic and anticholinesterase activities of Clitoria ternatea Linn. root extract: Potential treatment for cognitive decline

Damodaran, Thenmoly, See, Cheah Pike, Murugaiyah, Vikneswaran, Hassan, Zurina

Journal:

Neurochemistry International

Année:

2020

Fichier:

PDF, 6.43 MB

2020

24

Determination of four lignans in Phyllanthus niruri L. by a simple high-performance liquid chromatography method with fluorescence detection

Vikneswaran Murugaiyah, Kit-Lam Chan

Journal:

Journal of Chromatography A

Année:

2007

Langue:

english

Fichier:

PDF, 354 KB

english, 2007

25

Determination of mitragynine in plasma with solid-phase extraction and rapid HPLC–UV analysis, and its application to a pharmacokinetic study in rat

Suhanya Parthasarathy, Surash Ramanathan, Sabariah Ismail, Mohd Ilham Adenan, Sharif Mahsufi Mansor, Vikneswaran Murugaiyah

Journal:

Analytical and Bioanalytical Chemistry

Année:

2010

Langue:

english

Fichier:

PDF, 191 KB

english, 2010

26

Synthesis, Antimicrobial and Cholinesterase Enzymes Inhibitory Activities of Indeno Imidazoles and X-Ray Crystal Structure of 3a,8a-Dihydroxy-1,3-diphenyl-1,3,3a,8a-tetrahydro-indeno[1,2-d]imidazole-2,8-dione

Ghalib, Raza Murad, Hashim, Rokiah, Alshahateet, Solhe F., Mehdi, Sayed Hasan, Sulaiman, Othman, Chan, Kit-Lam, Murugaiyah, Vikneswaran, Jawad, Ali

Journal:

Journal of Chemical Crystallography

Année:

2012

Langue:

english

Fichier:

PDF, 495 KB

english, 2012

27

Synthesis, characterization, antimicrobial and enzymatic activity of 4b,9b-dihydroxy-7,8-dihydro-4bH-indeno[1,2-b]benzofuran-9,10(6H,9bH)-dione

Sayed Hasan Mehdi, Rokiah Hashim, Raza Murad Ghalib, M. Fátima C. Guedes da Silva, Othman Sulaiman, Syed Ziaur Rahman, Vikneswaran Murugaiyah, Mani Maran Marimuthu

Journal:

Journal of Molecular Structure

Année:

2011

Langue:

english

Fichier:

PDF, 942 KB

english, 2011

28

Synthesis, supramolecularity and in vitro antimicrobial activity of 3a,8a-dihydroxy-2-thioxo-1,3,3a,8a-tetrahydroindeno[1,2-d]imidazol-8(2H)-one

Raza Murad Ghalib, Rokiah Hashim, Solhe F. Alshahateet, Sayed Hasan Mehdi, Othman Sulaiman, Vikneswaran Murugaiyah, Claira Arul Aruldass

Journal:

Journal of Molecular Structure

Année:

2011

Langue:

english

Fichier:

PDF, 441 KB

english, 2011

29

Synthesis and discovery of novel piperidone-grafted mono- and bis-spirooxindole-hexahydropyrrolizines as potent cholinesterase inhibitors

Kia, Yalda, Osman, Hasnah, Kumar, Raju Suresh, Murugaiyah, Vikneswaran, Basiri, Alireza, Perumal, Subbu, Wahab, Habibah A., Bing, Choi Sy

Journal:

Bioorganic & Medicinal Chemistry

Année:

2013

Langue:

english

Fichier:

PDF, 1.03 MB

english, 2013

30

Effects of Mesua ferrea Leaf and Fruit Extracts on Growth and Morphology of Staphylococcus aureus

Aruldass, Claira Arul, Marimuthu, Mani Maran, Ramanathan, Surash, Mansor, Sharif Mahsufi, Murugaiyah, Vikneswaran

Journal:

Microscopy and Microanalysis

Année:

2013

Langue:

english

Fichier:

PDF, 6.06 MB

english, 2013

31

Synthesis and molecular modeling study of Cu(II) complexes derived from 2-(diphenylmethylene)hydrazinecarbothioamide derivatives with cholinesterase inhibitory activities

Chan, Yi Chen, Mohamed Ali, Abdussalam Salhin, Khairuddean, Melati, Khaw, Kooi Yeong, Murugaiyah, Vikneswaran, Basiri, Alireza

Journal:

Chinese Chemical Letters

Année:

2013

Langue:

english

Fichier:

PDF, 292 KB

english, 2013

32

Synthesis, characterization and cholinesterase enzymes inhibitory activity of 1-[3-methyl-5-(2,6,6-trimethyl-cyclohex-1-enyl)-4,5-dihydro-pyrazol-1-yl]-ethanone

Mehdi, Sayed Hasan, Ghalib, Raza Murad, Hashim, Rokiah, da Silva, M. Fátima C. Guedes, Sulaiman, Othman, Murugaiyah, Vikneswaran, Marimuthu, Mani Maran, Naqvi, Mehnaz

Journal:

Journal of Molecular Structure

Année:

2013

Langue:

english

Fichier:

PDF, 1.21 MB

english, 2013

33

An expedient, ionic liquid mediated multi-component synthesis of novel piperidone grafted cholinesterase enzymes inhibitors and their molecular modeling study

Basiri, Alireza, Murugaiyah, Vikneswaran, Osman, Hasnah, Kumar, Raju Suresh, Kia, Yalda, Awang, Khalijah Binti, Ali, Mohamed Ashraf

Journal:

European Journal of Medicinal Chemistry

Année:

2013

Langue:

english

Fichier:

PDF, 987 KB

english, 2013

34

Synthesis, characterization, and molecular docking analysis of novel benzimidazole derivatives as cholinesterase inhibitors

Yoon, Yeong Keng, Ali, Mohamed Ashraf, Wei, Ang Chee, Choon, Tan Soo, Khaw, Kooi-Yeong, Murugaiyah, Vikneswaran, Osman, Hasnah, Masand, Vijay H.

Journal:

Bioorganic Chemistry

Année:

2013

Langue:

english

Fichier:

PDF, 927 KB

english, 2013

35

Microwave assisted synthesis, cholinesterase enzymes inhibitory activities and molecular docking studies of new pyridopyrimidine derivatives

Basiri, Alireza, Murugaiyah, Vikneswaran, Osman, Hasnah, Kumar, Raju Suresh, Kia, Yalda, Ali, Mohamed Ashraf

Journal:

Bioorganic & Medicinal Chemistry

Année:

2013

Langue:

english

Fichier:

PDF, 1.42 MB

english, 2013

36

A facile chemo-, regio- and stereoselective synthesis and cholinesterase inhibitory activity of spirooxindole–pyrrolizine–piperidine hybrids

Kia, Yalda, Osman, Hasnah, Kumar, Raju Suresh, Murugaiyah, Vikneswaran, Basiri, Alireza, Perumal, Subbu, Razak, Ibrahim Abdul

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2013

Langue:

english

Fichier:

PDF, 894 KB

english, 2013

37

Cholinesterase inhibitory activity versus aromatic core multiplicity: A facile green synthesis and molecular docking study of novel piperidone embedded thiazolopyrimidines

Basiri, Alireza, Murugaiyah, Vikneswaran, Osman, Hasnah, Kumar, Raju Suresh, Kia, Yalda, Hooda, Alysha, Parsons, Richard B.

Journal:

Bioorganic & Medicinal Chemistry

Année:

2014

Langue:

english

Fichier:

PDF, 1.62 MB

english, 2014

38

Ionic liquid mediated synthesis of mono- and bis-spirooxindole-hexahydropyrrolidines as cholinesterase inhibitors and their molecular docking studies

kia, Yalda, Osman, Hasnah, Kumar, Raju Suresh, Basiri, Alireza, Murugaiyah, Vikneswaran

Journal:

Bioorganic & Medicinal Chemistry

Année:

2014

Langue:

english

Fichier:

PDF, 1.99 MB

english, 2014

39

Effect of extraction solvents and plant parts used on the antihyperlipidemic and antioxidant effects of Garcinia atroviridis : a comparative study

Al-Mansoub, Majed Ahmed, Asmawi, Mohd. Zaini, Murugaiyah, Vikneswaran

Journal:

Journal of the Science of Food and Agriculture

Année:

2014

Langue:

english

Fichier:

PDF, 102 KB

english, 2014

40

Corrigendum to ‘Synthesis, Characterization and Cholinesterase enzymes inhibitory activity of 1-[3-Methyl-5-(2,6,6-trimethyl-cyclohex-1-enyl)-4,5-dihydro-pyrazol-1-yl]-ethanone’ [MOLSTR 1049 (2013) 488–493]

Mehdi, Sayed Hasan, Ghalib, Raza Murad, Hashim, Rokiah, Guedes da Silva, M. Fátima C., Sulaiman, Othman, Murugaiyah, Vikneswaran, Marimuthu, Mani Maran, Naqvi, Mehnaz

Journal:

Journal of Molecular Structure

Année:

2013

Langue:

english

Fichier:

PDF, 236 KB

english, 2013

41

Synthesis and discovery of highly functionalized mono- and bis-spiro-pyrrolidines as potent cholinesterase enzyme inhibitors

Kia, Yalda, Osman, Hasnah, Suresh Kumar, Raju, Basiri, Alireza, Murugaiyah, Vikneswaran

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2014

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2014

42

New cholinesterase inhibitors from Garcinia atroviridis

Tan, Wen-Nee, Khairuddean, Melati, Wong, Keng-Chong, Khaw, Kooi-Yeong, Vikneswaran, Murugaiyah

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 1024 KB

english, 2014

43

Natural lipid-lowering agents and their effects: an update

Saghir, Sultan Ayesh Mohammed, Revadigar, Vageesh, Murugaiyah, Vikneswaran

Journal:

European Food Research and Technology

Année:

2014

Langue:

english

Fichier:

PDF, 388 KB

english, 2014

44

Ionic liquid mediated synthesis and molecular docking study of novel aromatic embedded Schiff bases as potent cholinesterase inhibitors

Abd Razik, Basma M., Osman, Hasnah, Basiri, Alireza, Salhin, Abdussalam, Kia, Yalda, Ezzat, Mohammed Oday, Murugaiyah, Vikneswaran

Journal:

Bioorganic Chemistry

Année:

2014

Langue:

english

Fichier:

PDF, 680 KB

english, 2014

45

Natural indole butyrylcholinesterase inhibitors from Nauclea officinalis

Liew, Sook Yee, Khaw, Kooi Yeong, Murugaiyah, Vikneswaran, Looi, Chung Yeng, Wong, Yi Li, Mustafa, Mohd Rais, Litaudon, Marc, Awang, Khalijah

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 734 KB

english, 2015

46

Cholinesterase inhibitory triterpenoids from the bark of Garcinia hombroniana

Jamila, Nargis, Khairuddean, Melati, Yeong, Khaw Kooi, Osman, Hasnah, Murugaiyah, Vikneswaran

Journal:

Journal of Enzyme Inhibition and Medicinal Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 318 KB

english, 2015

47

Neurohormetic phytochemicals: An evolutionary–bioenergetic perspective

Murugaiyah, Vikneswaran, Mattson, Mark P.

Journal:

Neurochemistry International

Année:

2015

Langue:

english

Fichier:

PDF, 881 KB

english, 2015

48

(3 E ,5 E )-3,5-Dibenzylidene-1-[3-(piperidin-1-yl)propanoyl]piperidin-4-one

Kia, Yalda, Osman, Hasnah, Murugaiyah, Vikneswaran, Hemamalini, Madhukar, Fun, Hoong-Kun

Journal:

Acta Crystallographica Section E Structure Reports Online

Année:

2011

Langue:

english

Fichier:

PDF, 816 KB

english, 2011

49

(3 E ,5 E )-1-Acryloyl-3,5-bis(2,4-dichlorobenzylidene)piperidin-4-one hemihydrate

Basiri, Alireza, Murugaiyah, Vikneswaran, Osman, Hasnah, Hemamalini, Madhukar, Fun, Hoong-Kun

Journal:

Acta Crystallographica Section E Structure Reports Online

Année:

2011

Langue:

english

Fichier:

PDF, 625 KB

english, 2011

50

(3 E ,5 E )-3,5-Bis(naphthalen-1-ylmethylidene)piperidin-4-one

Kia, Yalda, Osman, Hasnah, Murugaiyah, Vikneswaran, Arshad, Suhana, Razak, Ibrahim Abdul

Journal:

Acta Crystallographica Section E Structure Reports Online

Année:

2012

Langue:

english

Fichier:

PDF, 381 KB

english, 2012